** Description This document contains one of two graphs provided for the 2003 Graph Drawing Contest. It consists of a biological network representing the transcriptional regulation of Escherichia coli, i.e. nodes represent operons and transcription factors, and (directed) edges represent interactions. Note that there are loops (autoregulation). There is a string-valued node attribute (operon name) and an integer edge attribute (regulation type). Particularly interesting about this network is the frequent occurrence of small subgraphs, so-called motifs, described in Network motifs in the transcriptional regulation network of Escherichia coli S S SHEN-ORR, R MILO, S MANGAN and U ALON, Nature Genetics 31(1):64-68 How can a visualization highlight such motifs using graph drawing methods? Data courtesy of Uri Alon, The Weizmann Institute, Israel. ** DATA FORMAT no of nodes id_node1 name id_node2 name id_node3 name ... no of edges id_source_node id_target_node type ... where name is Name of operon type is 1: activator 2: repressor 3: dual